Alignment of Multiple Sequences of Amino Acids, using Genetic Algorithms

Authors

  • Luis Felipe Solanilla Universidad Icesi, Cali
  • Carlos Arturo Gómez Teshima Universidad Icesi, Cali
  • Luis Eduardo Múnera S. Universidad Icesi, Cali

DOI:

https://doi.org/10.18046/syt.v3i5.946

Keywords:

Bioinformatics, genetic algorithms, genomics, multiple sequence alignment.

Abstract

This article describes a genetic algorithm and its implementation that it allows the alignment of multiple sequences of amino acids by means of locations that simulate the gaps insertion (holes) and actions of recombination to obtain higher scores in the alignment. Such scores are obtained by means of the method of the sum of even, in which there are considered all the possible combinations of amino acids in each column of the alignment and they are qualified being based on the punctuations of the matrix BLOSUM62.

Author Biographies

  • Luis Felipe Solanilla, Universidad Icesi, Cali
    Bio Statement available in Spanish
  • Carlos Arturo Gómez Teshima, Universidad Icesi, Cali
    Not available
  • Luis Eduardo Múnera S., Universidad Icesi, Cali
    Bio Statement available in Spanish

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Published

2006-10-11

Issue

Section

Original Research