Acute Kidney Injury (AKI) is a sudden onset of kidney failure and damage marked by an increase in the serum creatinine levels (amongst other biomarkers) of the patient. Kidney Disease Improving Global Outcomes (KDIGO) has a set of guidelines and standard definitions of AKI:
Stage 1: 50% increase in creatinine in < 7 days or 0.3 increase in creatinine in < 48 hours
Stage 2: 100% increase in (or doubling of) creatinine in < 7 days
Stage 3: 200% increase in (or tripling of) creatinine in < 7 days
This package contains a flagger to determine if a patient has developed AKI based on longitudinal data of serum creatinine measurements.
The package can be installed via CRAN.
install.packages("akiFlagger")Alternatively, you can install the development version of the package from GitHub with:
# install.packages("devtools")
devtools::install_github("isaranwrap/akiFlagger")There is a walk-through vignette available on Github to introduce the necessary components and parameters of the flagger. The notebook has also been adapted in the documentation.